Doxycycline Hyclate(24390-14-5)
Product Description
● Doxycycline Hcl is antibacterial spectrum iri pedyo zvikuru neTetracycline neTerramycin, asi ine mhedzisiro iri nani, iva nehanya neStaphylococcus Aureus ye tetracycline-resistant, oxytetracycline, inogara kwenguva refu.Inowanzoshandiswa muSenile Chronic Bronchitis, chirwere chekufema, utachiona hwemapapu, acute tonsillitis, mycoplasma mabayo, weti turakiti utachiona, muchetura ropa, bacillary dysentery, acute lymphadenitis, etc. Inonyanya kufarirwa kune Nephropathy murwere nekuda kwechepfu yayo isingaonekwi yeitsvo.
● Doxycycline Hyclate is the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic inoratidzira antimicrobial activity.Doxycycline hyclate inosunga ichidzokera kumashure ku30S ribosomal subunit, zvichida kune 50S ribosomal subunit zvakare, nokudaro ichivharira kusunga kweaminoacyl-tRNA kune mRNA-ribosome complex.Izvi zvinotungamirira kukudzivirira kweprotein synthesis.Mukuwedzera, mumiririri uyu akaratidza kuvharidzirwa kwebasa re collagenase.
Application
Doxycycline Hyclate inoshandiswa kurapa zvirwere zvakasiyana-siyana zvebhakitiriya, kusanganisira izvo zvinokonzera acne.Doxycycline Hyclate inoshandiswawo kudzivirira marariya.Doxycycline Hyclate inozivikanwa se tetracycline antibiotic.Inoshanda nekumisa kukura kwebhakitiriya.Mushonga unorwisa mabhakitiriya unorapa zvirwere zvemabhakitiriya chete.
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | Yellow crystalline powder | Conforms |
| Identification | TLC | Conforms |
| sulfuric acid reaction a yellow color inokura | Conforms | |
| inopa maitiro ekloridi | Conforms | |
| PH | 2.0~3.0 | 2.3 |
| Specific absorbance | pa 349nm e(1%) 300~355 | 320 |
| Specific optical rotation | -105 ~ -120° | -110° |
| Heavy metals: | ≤50ppm | <20ppm |
| Chiedza chinotora tsvina | pa490nm ≤0.07 | 0.03 |
| Zvinhu zvinoenderana | 6-epidoxycycline ≤2.0%metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) chero kumwe kusachena ≤0.5% tsvina isingazivikanwe ≤0.1% (ep5) | 1.6%0.1% Kusawanikwa Kusawanikwa Kusawanikwa Kusawanikwa Kusawanikwa |
| Ethanol | 4.3~6.0% (m/m) | 4.5% |
| Sulfate ash | ≤0.4% | 0.05% |
| Mvura | 1.4 ~ 2.8% | 1.8% |
| Assay | 95.0 ~ 102.0% ( c22h25cln2o8) zvichibva pane anhydrous, ethanol-isina chinhu | 98.6% |
| Mhedziso | Inoenderana neUSP32 | |
