Tranexamic Acid(1197-18-8)
Product Description
● Tranexamic Acid(1197-18-8)
● CAS Nha.: · 1197-18-8
● EINECS Nha.: 356.2222
● MF: C8H15NO2
● Package: 25Kg / Drum
● Tranexamic acid (TXA) mushonga unoshandiswa kurapa kana kudzivirira kurasikirwa neropa rakawandisa kubva mukukuvadzwa kukuru, kubuda ropa mushure mekusununguka, kuvhiyiwa, kubvisa mazino, kubuda ropa mumhino, uye kuenda kumwedzi kwakanyanya.[2][3]Inoshandiswawo pakugara nhaka angioedema. [2][4]Inotorwa nemuromo kana nejekiseni mutsinga.
Nzira yekuita
Tranexamic asidhi inogadzirwa analogi yeamino acid lysine.Inoshanda senge antifibrinolytic nekudzoreredza kusunga mana kusvika mashanu lysine receptor nzvimbo paplasminogen.Izvi zvinoderedza kutendeuka kweplasminogen kuita plasmin, kudzivirira kuparara kwefibrin uye kuchengetedza chimiro chefibrin's matrix structure.Tranexamic acid ine kasere kuita antifibrinolytic yeanalogue yekare, ε-aminocaproic acid.[citation inodiwa] Tranexamic acid inodzivisawo zvakananga basa replasmin rine simba risina simba (IC50 = 87 mM), uye rinogona kuvhara-inoshanda-saiti yeurokinase plasminogen activator (uPA) nepamusoro-soro (Ki = 2 mM), imwe yepamusoro-soro pakati peserine proteases.
Tranexamic acid inoshanda
Tranexamic acid inowanzoshandiswa zvichitevera kukuvadzwa kukuru.[13]Tranexamic acid inoshandiswa kudzivirira nekurapa kurasikirwa neropa mumamiriro ezvinhu akasiyana-siyana, senge mazino, kubuda ropa kwakanyanya, uye kuvhiyiwa kune njodzi huru yekurasikirwa neropa.
| Zvinhu zveMuedzo | Pharmacopeial Criteria | Test Result | |
| VANHU | Kuonekwa: Ichena kana inenge yakachena, crystalline powder | White crystalline powder | |
| Solubility: Inonyungudika zvakasununguka mumvura uye muglacial acetic acid, isinganyunguriki muacetone uye mu ethanol (96%). | Pass | ||
| KUZIVA | Infrared Absorption Spectrophotometry: IR spectrum iri mukuwirirana neTranexamic acid CRS. | Pass | |
| TEST | pH (2,2.3) | 7.0 〜8.0 | 7.4 |
| Zvinhu zvinoenderana (HPLC2.2.29) | Kusachena A≤ 0.1 % | Haina Kuonekwa | |
| Kusachena B≤ 0.2% | 0.03% | ||
| ImpuritiesC Hutsvina husina kutaurwa≤ 0.10% Hutsvina D Zvimwe Zvisina Kuchena | 0.002% 0.001% Haina Kuonekwa | ||
| Huwandu hwetsvina isina kutaurwa≤ 0.2% | 0.003% | ||
| Halides Inoratidzwa seChlorides | ≤140ppm | <140ppm | |
| Kurasika paKuomesa | ≤0.5% | 0.026% | |
| Sulfated Ash | ≤0.1% | 0.027% | |
| ASSAY | Inofanira kunge iri mukati (yakaomeswa yakavakirwa) 99.0% 〜101.0% | 100.1% | |
